Article
Genetic association analysis of behavioral inhibition using candidate loci from mouse models.
American journal of medical genetics - 8 Apr 2001
Smoller J W, Rosenbaum J F, Biederman J, Susswein L S, Kennedy J, Kagan J, Snidman N, Laird N, Tsuang M T, Faraone S V, Schwarz A, Slaugenhaupt S A
Abstract excerpt
Genes influence the development of anxiety disorders, but the specific loci involved are not known. Genetic association studies of anxiety disorders are complicated by the complexity of the phenotypes and the difficulty in identifying appropriate candidate loci. We have begun to examine the genetics of behavioral inhibition to the unfamiliar (BI), a heritable temperamental predisposition that is a developmental...
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