Article
Multiple origins of replication contribute to a discontinuous pattern of DNA synthesis across the T4 genome during infection.
Journal of molecular biology - 27 Apr 2007
Brister J Rodney, Nossal Nancy G
Abstract excerpt
Chromosomes provide a template for a number of DNA transactions, including replication and transcription, but the dynamic interplay between these activities is poorly understood at the genomic level. The bacteriophage T4 has long served as a model for the study of DNA replication, transcription, and recombination, and should be an excellent model organism in which to integrate in vitro biochemistry into a...
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