Article

Population-wide Screening for Germline Variants of Hereditary Cancer Genes in 12K Unselected Japanese Colorectal Cancers and 27K Controls

2020-03-17

Abstract excerpt

<h4>Background & Aims</h4> Colorectal cancer (CRC) is one of the most common cancers in Western countries and Japan. Currently, a few % of CRCs can be attributed to recognizable hereditary germline variants of known CRC susceptibility genes, predominantly the DNA mismatch repair genes. To establish a universal screening strategy for hereditary CRCs, it is necessary to explore the prevalence of hereditary CRC and...

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Literature Corpus work: 98db811c-a35c-50dd-9cc8-bcc86f7b6dca
DOI: 10.1101/2020.03.15.989947

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Population-wide Screening for Germline Variants of Hereditary Cancer Genes in 12K Unselected Japanese Colorectal Cancers and 27K ControlsDOI 10.1101/2020.03.15.989947Read

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