Article
Population-based Screening for Hereditary Colorectal Cancer Variants in Japan.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Sept 2022
Fujita Masashi, Liu Xiaoxi, Iwasaki Yusuke, Terao Chikashi, Mizukami Keijiro, Kawakami Eiryo, Takata Sadaaki, Inai Chihiro, Aoi Tomomi, Mizukoshi Misaki, Maejima Kazuhiro, Hirata Makoto, Murakami Yoshinori, Kamatani Yoichiro, Kubo Michiaki, Akagi Kiwamu, Matsuda Koichi, Nakagawa Hidewaki, Momozawa Yukihide
Abstract excerpt
BACKGROUND & AIMS: Colorectal cancer (CRC) is one of the most common cancers in the world. A small proportion of CRCs can be attributed to recognizable hereditary germline variants of known CRC susceptibility genes. To better understand cancer risk, it is necessary to explore the prevalence of hereditary CRC and pathogenic variants of multiple cancer-predisposing genes in non-European populations. METHODS: We...
Topics
- Colorectal Neoplasms
- Early Detection of Cancer
- Genetic Predisposition to Disease
- Genetic Testing
- Germ-Line Mutation
- Humans
- Japan