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Article

AQP4 tag single nucleotide polymorphisms in patients with traumatic brain injury.

Journal of neurotrauma - 1 Dec 2014

Dardiotis Efthimios, Paterakis Konstantinos, Tsivgoulis Georgios, Tsintou Magdalini, Hadjigeorgiou Georgios F, Dardioti Maria, Grigoriadis Savas, Simeonidou Constantina, Komnos Apostolos, Kapsalaki Eftychia, Fountas Kostas, Hadjigeorgiou Georgios M

Abstract excerpt

Accumulating evidence suggests that the extent of brain injury and the clinical outcome after traumatic brain injury (TBI) are modulated, to some degree, by genetic variants. Aquaporin-4 (AQP4) is the predominant water channel in the central nervous system and plays a critical role in controlling the water content of brain cells and the development of brain edema after TBI. We sought to investigate the influence...

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Identifiers

PMID: 24999750
DOI: 10.1089/neu.2014.3347
PMCID: PMC4238262

Genes

AQP4

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