Article
Association Between the Single Nucleotide Polymorphism and the Level of Aquaporin-4 Protein Expression in Han and Minority Chinese with Inflammatory Demyelinating Diseases of the Central Nervous System.
Molecular neurobiology - 1 Jul 2016
Chu Lan, Dai Qingqing, Xu Zhu, He Dian, Wang Hao, Wang Qingsong, Zhang Yifan, Zhu Yingwu, Li Yuan, Cai Gang, Slavica Krantic, Allan Kermode
Abstract excerpt
The purpose of this study was to determine whether or not aquaporin-4 (AQP4) gene mutations are related to the pathogenesis of inflammatory demyelinating diseases in the central nervous system. Polymorphisms of AQP4 exons 1-5 were determined by sequencing DNA from 67 patients with central nervous system inflammatory demyelinating diseases, including neuromyelitis optica (NMO), multiple sclerosis, recurrent or...
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