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Article

Chloroquine-resistance molecular markers (Pfcrt T76 and Pfmdr-1 Y86) and amodiaquine resistance in Burkina Faso.

Tropical medicine & international health : TM & IH - 1 Feb 2008

Tinto Halidou, Guekoun Lougué, Zongo Issaka, Guiguemdé Robert Tinga, D'Alessandro Umberto, Ouédraogo Jean Bosco

Abstract excerpt

We investigated the relationship between the two main molecular markers for chloroquine resistance (Pfcrt T76 and Pfmdr-1 Y86) and the clinical efficacy of amodiaquine in Burkina Faso. Before treatment, the prevalence of Pfcrt T76, Pfmdr-1 Y86 or both mutations in the same infection was significantly higher in patients who experienced a recrudescence than in those who successfully responded to the treatment....

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PMID: 18304270
DOI: 10.1111/j.1365-3156.2007.01995.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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