Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic of plasmodium falciparum chloroquine resistance transporter gene Pfcrt K76T mutation five years after withdrawal of chloroquine in Burkina Faso.

The Pan African medical journal - 1 Jan 2015

Sondo Paul, Derra Karim, Tarnagda Zekiba, Nakanabo Seydou Diallo, Zampa Odile, Kazienga Adama, Valea Innocent, Sorgho Hermann, Ouedraogo Jean-Bosco, Guiguemde Tinga Robert, Tinto Halidou

Abstract excerpt

We investigated the evolution of Pfcrt K76T mutation five years after the withdrawal of chloroquine in Burkina Faso. A total of 675 clinical isolates collected from October 2010 to September 2012 were successfully genotyped. Single nucleotide polymorphism in Pfcrt (codon 76) gene was analyzed. The prevalence of resistant Pfcrt 76T allele was 20.55%. There was a progressive decrease of the proportion of mutant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimalarials
Share to Burkina Faso

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chloroquine

Share to Drug Resistance

Share to Malaria, Falciparum

Share to Membrane Transport Proteins

Share to Plasmodium falciparum

Share to Protozoan Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 26516402
DOI: 10.11604/pamj.2015.21.101.6437
PMCID: PMC4606025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic of plasmodium falciparum chloroquine resistance transporter gene Pfcrt K76T mutation five years after withdrawal of chloroquine in Burkina Faso.PMID 26516402Read ↗

Chloroquine sensitivity: diminished prevalence of chloroquine-resistant gene marker pfcrt-76 13 years after cessation of chloroquine use in Msambweni, KenyaSemantic proximity Read ↗

Reemergence of chloroquine-sensitive pfcrt K76 Plasmodium falciparum genotype in southeastern Cameroon.Semantic proximity Read ↗

High prevalence of PfCRT K76T mutation in Plasmodium falciparum isolates in Ghana.Semantic proximity Read ↗

Temporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal KenyaSemantic proximity Read ↗

Polymorphisms in Pfcrt and Pfmdr-1 genes after five years withdrawal of chloroquine for the treatment of Plasmodium falciparum malaria in West Bengal, India.Semantic proximity Read ↗

Declining Frequency of Chloroquine-resistant Haplotype of <em>Plasmodium falciparum</em> (CVIET) in an Endemic Area of Southwest Nigeria 17 Years After Withdrawal of ChloroquineSemantic proximity Read ↗

The return of chloroquine-sensitive Plasmodium falciparum parasites in Jazan region, southwestern Saudi Arabia over a decade after the adoption of artemisinin-based combination therapy: analysis of genetic mutations in the pfcrt gene.Semantic proximity Read ↗

Recovery and stable persistence of chloroquine sensitivity in Plasmodium falciparum parasites after its discontinued use in Northern UgandaSemantic proximity Read ↗

Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania.Semantic proximity Read ↗

The return of chloroquine-sensitive Plasmodium falciparum parasites in Jazan Region, Southwestern Saudi Arabia over a decade after the adoption of artemisinin-based combination therapy: analysis of genetic mutations in the pfcrt geneSemantic proximity Read ↗

Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi.Semantic proximity Read ↗

Expansion of wild type allele rather than back mutation in pfcrt explains the recent recovery of chloroquine sensitivity of Plasmodium falciparum in Malawi.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.