Article
Association of Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) Gene Polymorphisms with Autoimmune Thyroid Disease in Children and Adults: Case-Control Study.
PloS one - 1 Jan 2016
Ting Wei-Hsin, Chien Ming-Nan, Lo Fu-Sung, Wang Chao-Hung, Huang Chi-Yu, Lin Chiung-Ling, Lin Wen-Shan, Chang Tzu-Yang, Yang Horng-Woei, Chen Wei-Fang, Lien Ya-Ping, Cheng Bi-Wen, Lin Chao-Hsu, Chen Chia-Ching, Wu Yi-Lei, Hung Chen-Mei, Li Hsin-Jung, Chan Chon-In, Lee Yann-Jinn
Abstract excerpt
Autoimmune thyroid disease (AITD), including Graves disease (GD) and Hashimoto disease (HD), is an organ-specific autoimmune disease with a strong genetic component. Although the cytotoxic T-lymphocyte-associated protein 4 (CTLA4) polymorphism has been reported to be associated with AITD in adults, few studies have focused on children. The aim of our study was to investigate whether the CTLA4 polymorphisms,...
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