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Article

Allelic lineages of the ficolin genes (FCNs) are passed from ancestral to descendant primates.

PloS one - 1 Jan 2011

Hummelshøj Tina, Nissen Janna, Munthe-Fog Lea, Koch Claus, Bertelsen Mads Frost, Garred Peter

Abstract excerpt

The ficolins recognize carbohydrates and acetylated compounds on microorganisms and dying host cells and are able to activate the lectin pathway of the complement system. In humans, three ficolin genes have been identified: FCN1, FCN2 and FCN3, which encode ficolin-1, ficolin-2 and ficolin-3, respectively. Rodents have only two ficolins designated ficolin-A and ficolin-B that are closely related to human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22194813
DOI: 10.1371/journal.pone.0028187
PMCID: PMC3240626

Genes

FCN1
FCN3
FCN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Allelic lineages of the ficolin genes (FCNs) are passed from ancestral to descendant primates.PMID 22194813Read ↗

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