Article
SNF4Agamma, the Drosophila AMPK gamma subunit is required for regulation of developmental and stress-induced autophagy.
Autophagy - 1 May 2008
Lippai Mónika, Csikós György, Maróy Péter, Lukácsovich Tamás, Juhász Gábor, Sass Miklós
Abstract excerpt
In holometabolous insects including Drosophila melanogaster a wave of autophagy triggered by 20-hydroxyecdysone is observed in the larval tissues during the third larval stage of metamorphosis. We used this model system to study the genetic regulation of autophagy. We performed a genetic screen to select P-element insertions that affect autophagy in the larval fat body. Light and electron microscopy of one of the...
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