Article
Association analysis of allelic variants of USF1 in coronary atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology - 1 May 2008
Kristiansson Kati, Ilveskoski Erkki, Lehtimäki Terho, Peltonen Leena, Perola Markus, Karhunen Pekka J
Abstract excerpt
OBJECTIVE: USF1 regulates the transcription of more than 40 cardiovascular related genes and is well established as a gene associated with familial combined hyperlipidemia, a condition increasing the risk for coronary heart disease. No detailed data, however, exists on the impact of this gene to the critical outcome at the tissue level: different types of atherosclerotic lesions. METHODS AND RESULTS: We analyzed...
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