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Article

Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1).

Nature genetics - 1 Apr 2004

Pajukanta Päivi, Lilja Heidi E, Sinsheimer Janet S, Cantor Rita M, Lusis Aldons J, Gentile Massimiliano, Duan Xiaoqun Joyce, Soro-Paavonen Aino, Naukkarinen Jussi, Saarela Janna, Laakso Markku, Ehnholm Christian, Taskinen Marja-Riitta, Peltonen Leena

Abstract excerpt

Familial combined hyperlipidemia (FCHL), characterized by elevated levels of serum total cholesterol, triglycerides or both, is observed in about 20% of individuals with premature coronary heart disease. We previously identified a locus linked to FCHL on 1q21-q23 in Finnish families with the disease. This region has also been linked to FCHL in families from other populations as well as to type 2 diabetes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 14991056
DOI: 10.1038/ng1320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1).PMID 14991056Read ↗

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