Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic association and interaction analysis of USF1 and APOA5 on lipid levels and atherosclerosis.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2010

Laurila Pirkka-Pekka, Naukkarinen Jussi, Kristiansson Kati, Ripatti Samuli, Kauttu Tuuli, Silander Kaisa, Salomaa Veikko, Perola Markus, Karhunen Pekka J, Barter Philip J, Ehnholm Christian, Peltonen Leena

Abstract excerpt

OBJECTIVE: USF1 is a ubiquitous transcription factor governing the expression of numerous genes of lipid and glucose metabolism. APOA5 is a well-established candidate gene regulating triglyceride (TG) levels and has been identified as a downstream target of upstream stimulatory factor. No detailed studies about the effect of APOA5 on atherosclerotic lesion formation have been conducted, nor has its potential...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aorta, Abdominal
Share to Aortic Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Apolipoprotein A-V

Share to Apolipoproteins A

Share to Autopsy

Share to Dyslipidemias

Share to Fibrosis

Share to Upstream Stimulatory Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 19910639
DOI: 10.1161/ATVBAHA.109.188912
PMCID: PMC3224996

Genes

APOA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic association and interaction analysis of USF1 and APOA5 on lipid levels and atherosclerosis.PMID 19910639Read ↗

Upstream Transcription Factor 1 (USF1) allelic variants regulate lipoprotein metabolism in women and USF1 expression in atherosclerotic plaque.Semantic proximity Read ↗

Association analysis of allelic variants of USF1 in coronary atherosclerosis.Semantic proximity Read ↗

Gene-gene interaction between APOA5 and USF1: two candidate genes for the metabolic syndrome.Semantic proximity Read ↗

USF1 and dyslipidemias: converging evidence for a functional intronic variant.Semantic proximity Read ↗

Association of USF1 and APOA5 polymorphisms with familial combined hyperlipidemia in an Italian population.Semantic proximity Read ↗

Genetics of familial combined hyperlipidemiaSemantic proximity Read ↗

USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease.Semantic proximity Read ↗

Functional variant disrupts insulin induction of USF1: mechanism for USF1-associated dyslipidemias.Semantic proximity Read ↗

USF1 gene variants, cardiovascular risk, and mortality in European Americans: analysis of two US cohort studies.Semantic proximity Read ↗

Variation in USF1 shows haplotype effects, gene : gene and gene : environment associations with glucose and lipid parameters in the European Atherosclerosis Research Study II.Semantic proximity Read ↗

The rs2516839 Polymorphism of the USF1 Gene May Modulate Serum Triglyceride Levels in Response to Cigarette Smoking.Semantic proximity Read ↗

Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.