USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease.

doi:10.1161/ATVBAHA.107.151530

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Article

USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease.

Arteriosclerosis, thrombosis, and vascular biology - 1 Oct 2007

Lee Jenny C, Weissglas-Volkov Daphna, Kyttälä Mira, Sinsheimer Janet S, Jokiaho Anne, de Bruin Tjerk W A, Lusis Aldons J, Brennan Marie-Luise, van Greevenbroek Marleen M J, van der Kallen Carla J H, Hazen Stanley L, Pajukanta Päivi

Abstract excerpt

OBJECTIVE: Familial combined hyperlipidemia (FCHL) characterized by high serum total cholesterol and/or triglycerides (TGs) is a common dyslipidemia predisposing to coronary artery disease (CAD). Recently, the upstream transcription factor 1 (USF1) was linked and associated with FCHL and TGs in Finnish FCHL families. Here we examined the previously associated rs3737787 SNP in extended Dutch FCHL families (n=532)...

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PMID: 17673701
DOI: 10.1161/ATVBAHA.107.151530

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