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Article

UGT1A7 haplotype is associated with an increased risk of hepatocellular carcinoma in hepatitis B carriers.

Cancer science - 1 Feb 2008

Kong Sun-Young, Ki Chang-Seok, Yoo Byung Chul, Kim Jong-Won

Abstract excerpt

The UGT1A7 gene encodes UDP-glucuronosyltransferase, a key enzyme catalyzing the glucuronidation of various carcinogens. In this study, we investigated the association between haplotypes of the whole UGT1A7 gene and the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B. Sequence analysis of exon1 and the promoter region of the UGT1A7 gene was carried out to determine haplotype profiles...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucuronosyltransferase

Share to Hepatitis B, Chronic

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Share to Promoter Regions, Genetic

Source

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Identifiers

PMID: 18271934
DOI: 10.1111/j.1349-7006.2007.00693.x
PMCID: PMC11159405

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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