Article
UDP-glucuronosyltransferase 1A7 genetic polymorphisms are associated with hepatocellular carcinoma risk and onset age.
The American journal of gastroenterology - 1 Aug 2005
Tseng Chien-Sen, Tang Kung-Sheng, Lo Hoi-Wan, Ker Chen-Guo, Teng Hsiu-Chen, Huang Ching-Shan
Abstract excerpt
OBJECTIVES: It has been demonstrated that the UDP-glucuronosyltransferase (UGT) 1A7*3 allele is a risk factor for hepatocellular carcinoma (HCC) in German and Japanese populations. In this study, therefore, we evaluated the association between UGT1A7 genetic polymorphisms and HCC risk in southern Taiwan, where hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are endemic. METHODS: The 217 HCC...
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