Article
A common 8q24 variant and the risk of colon cancer: a population-based case-control study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 2008
Li Li, Plummer Sarah J, Thompson Cheryl L, Merkulova Alona, Acheson Louise S, Tucker Thomas C, Casey Graham
Abstract excerpt
Three recent studies identified common variants on 8q24 that confer modestly increased susceptibility to colorectal cancer. Here, we replicate the association in a population-based case-control study of colon cancer, including 561 cases and 721 unrelated controls. The rs6983267 marker was significantly associated with colon cancer risk. Compared with those homozygous for the T allele, the heterozygous and...
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