Genetic variants on chromosome 8q24 and colorectal neoplasia risk: a case-control study in China and a meta-analysis of the published literature.

doi:10.1371/journal.pone.0018251

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Genetic variants on chromosome 8q24 and colorectal neoplasia risk: a case-control study in China and a meta-analysis of the published literature.

PloS one - 24 Mar 2011

Li Mian, Zhou Yanhong, Chen Peizhan, Yang Huan, Yuan Xiaoyan, Tajima Kazuo, Cao Jia, Wang Hui

Abstract excerpt

Previous studies have found that common genetic variants on chromosome 8q24 are associated with the risk of developing colorectal neoplasia. We conducted a hospital-based case-control study, including 435 cases and 788 unrelated controls to investigate the associations between common variants on 8q24 and the risk of colorectal cancer in a Chinese population. We also evaluated the association of rs6983267 with...

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PMID: 21455501
DOI: 10.1371/journal.pone.0018251
PMCID: PMC3063839

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