Article
Mismatch repair in Trypanosoma brucei: heterologous expression of MSH2 from Trypanosoma cruzi provides new insights into the response to oxidative damage.
Gene - 31 Mar 2008
Machado-Silva Alice, Teixeira Santuza M R, Franco Glória R, Macedo Andréa M, Pena Sérgio D J, McCulloch Richard, Machado Carlos Renato
Abstract excerpt
Trypanosomes are unicellular eukaryotes that cause disease in humans and other mammals. Trypanosoma cruzi and Trypanosoma brucei are the causative agents, respectively, of Chagas disease in the Americas and sleeping sickness in sub-Saharan Africa. To better comprehend the interaction of these parasites with their hosts, understanding the mechanisms involved in the generation of genetic variability is critical....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.