Article

Deciphering the interstrand crosslink DNA repair network expressed by <i>Trypanosoma brucei</i>

2019-02-08

Abstract excerpt

Interstrand crosslinks (ICLs) represent a highly toxic form of DNA damage that can block essential biological processes including DNA replication and transcription. To combat their deleterious effects all eukaryotes have developed cell cycle-dependent repair strategies that coopt various factors from ‘classical’ DNA repair pathways to resolve such lesions. Here, we report that Trypanosoma brucei , the causative a...

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Literature Corpus work: 15a9e0f2-5290-5495-9868-133178d84136
DOI: 10.1101/543975

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