Article
Mismatch repair regulates homologous recombination, but has little influence on antigenic variation, in Trypanosoma brucei.
The Journal of biological chemistry - 14 Nov 2003
Bell Joanna S, McCulloch Richard
Abstract excerpt
Antigenic variation is critical in the life of the African trypanosome, as it allows the parasite to survive in the face of host immunity and enhance its transmission to other hosts. Much of trypanosome antigenic variation uses homologous recombination of variant surface glycoprotein (VSG)-encodi...
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