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Overview of DNA Repair in <i>Trypanosoma cruzi, Trypanosoma brucei,</i> and <i>Leishmania major</i>

1 Jan 2010

Abstract excerpt

A wide variety of DNA lesions arise due to environmental agents, normal cellular metabolism, or intrinsic weaknesses in the chemical bonds of DNA. Diverse cellular mechanisms have evolved to maintain genome stability, including mechanisms to repair damaged DNA, to avoid the incorporation of modified nucleotides, and to tolerate lesions (translesion synthesis). Studies of the mechanisms related to DNA metabolism...

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PMID: 20976268
DOI: 10.4061/2010/840768

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