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Article

Arabidopsis GNARLED encodes a NAP125 homolog that positively regulates ARP2/3.

Current biology : CB - 10 Aug 2004

El-Assal Salah El-Din, Le Jie, Basu Dipanwita, Mallery Eileen L, Szymanski Daniel B

Abstract excerpt

In migrating cells, the actin filament nucleation activity of ARP2/3 is an essential component of dynamic cell shape change and motility. In response to signals from the small GTPase Rac1, alterations in the composition and/or subcellular localization of the WAVE complex lead to ARP2/3 activation. The human WAVE complex subunit, WAVE1/SCAR1, was first identified in Dictyostelium and is a direct ARP2/3 activator....

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PMID: 15296760
DOI: 10.1016/j.cub.2004.06.062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Arabidopsis GNARLED encodes a NAP125 homolog that positively regulates ARP2/3.PMID 15296760Read ↗

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