Article
Contiguous binding of decylsulfate on the interface-binding surface of pancreatic phospholipase A2.
Biochemistry - 4 Mar 2008
Bai Shi, Jain Mahendra K, Berg Otto G
Abstract excerpt
Pig pancreatic IB phospholipase A 2 (PLA2) forms three distinguishable premicellar E i (#) ( i = 1, 2, and 3) complexes at successively higher decylsulfate concentrations. The Hill coefficient for E 1 (#) is n 1 = 1.6, and n 2 and n 3 for E 2 (#) and E 3 (#) are about 8 each. Saturation-transfer difference nuclear magnetic resonance (NMR) and other complementary results with PLA2 show that decylsulfate molecules...
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