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Article

Guided reconstitution of membrane protein fragments.

Biopolymers - 1 Jan 2014

Cohen Leah S, Arshava Boris, Kauffman Sarah, Mathew Elizabeth, Fracchiolla Katrina E, Ding Fa-Xiang, Dumont Mark E, Becker Jeffrey M, Naider Fred

Abstract excerpt

Structural analysis by NMR of G protein-coupled receptors (GPCRs) has proven to be extremely challenging. To reduce the number of peaks in the NMR spectra by segmentally labeling a GPCR, we have developed a Guided Reconstitution method that includes the use of charged residues and Cys activation...

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PMID: 23897574
DOI: 10.1002/bip.22349
PMCID: PMC4246424

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23897574-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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