Article
Interfacial exclusion pressure determines the ability of apolipoprotein A-IV truncation mutants to activate cholesterol ester transfer protein.
The Journal of biological chemistry - 14 Jun 2002
Weinberg Richard B, Anderson Rachel A, Cook Victoria R, Emmanuel Florence, Denèfle Patrice, Tall Alan R, Steinmetz Armin
Abstract excerpt
We used a panel of recombinant human apolipoprotein (apo) A-IV truncation mutants, in which pairs of 22-mer alpha-helices were sequentially deleted along the primary sequence, to examine the impact of protein structure and interfacial activity on the ability of apoA-IV to activate cholesterol est...
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