Article
Cerebral cortical arteriolar angiopathy, vascular beta-amyloid, smooth muscle actin, Braak stage, and APOE genotype.
Stroke - 1 Mar 2008
Stopa Edward G, Butala Parag, Salloway Stephen, Johanson Conrad E, Gonzalez Liliana, Tavares Rosemarie, Hovanesian Virginia, Hulette Christine M, Vitek Michael P, Cohen Ronald A
Abstract excerpt
BACKGROUND AND PURPOSE: We examined the associations among the vascular beta-amyloid levels, smooth muscle actin, wall thickness, and lumen diameter to achieve greater understanding of the arteriolar changes that accompany Alzheimer disease (AD). METHODS: Post-mortem pathology brain specimens from 76 patients with AD and 19 non-AD age control subjects were studied. We analyzed arterioles of the frontal cortex...
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