Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals.

doi:10.1177/0271678X15621574

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Article

Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Jan 2017

Ighodaro Eseosa T, Abner Erin L, Fardo David W, Lin Ai-Ling, Katsumata Yuriko, Schmitt Frederick A, Kryscio Richard J, Jicha Gregory A, Neltner Janna H, Monsell Sarah E, Kukull Walter A, Moser Debra K, Appiah Frank, Bachstetter Adam D, Van Eldik Linda J, Nelson Peter T

Abstract excerpt

Risk factors and cognitive sequelae of brain arteriolosclerosis pathology are not fully understood. To address this, we used multimodal data from the National Alzheimer's Coordinating Center and Alzheimer's Disease Neuroimaging Initiative data sets. Previous studies showed evidence of distinct neurodegenerative disease outcomes and clinical-pathological correlations in the "oldest-old" compared to younger...

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PMID: 26738751
DOI: 10.1177/0271678X15621574
PMCID: PMC5363738

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