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Article

Brain arterial aging and its relationship to Alzheimer dementia.

Neurology - 19 Apr 2016

Gutierrez Jose, Honig Lawrence, Elkind Mitchell S V, Mohr Jay P, Goldman James, Dwork Andrew J, Morgello Susan, Marshall Randolph S

Abstract excerpt

OBJECTIVE: To test the hypothesis that brain arterial aging is associated with the pathologic diagnosis of Alzheimer disease (AD). METHODS: Brain large arteries were assessed for diameter, gaps in the internal elastic lamina (IEL), luminal stenosis, atherosclerosis, and lumen-to-wall ratio. Elastin, collagen, and amyloid were assessed with Van Gieson, trichrome, and Congo red staining intensities, and quantified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26984942
DOI: 10.1212/WNL.0000000000002590
PMCID: PMC4836884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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