Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prm3, the Fourth Gene in the Mouse Protamine Gene Cluster, Encodes a Conserved Acidic Protein That Affects Sperm Motility1

7 Feb 2008

Abstract excerpt

The protamine gene cluster containing the Prm1, Prm2, Prm3, and Tnp2 genes is present in humans, mice, and rats. The Prm1, Prm2, and Tnp2 genes have been extensively studied, but almost nothing is known about the function and regulation of the Prm3 gene. Here we demonstrate that an intronless Prm3 gene encoding a distinctive small acidic protein is present in 13 species from seven orders of mammals. We also...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Genetics and Reproduction
Share to RNA Research and Splicing
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18256328
DOI: 10.1095/biolreprod.107.065706

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prm3, the Fourth Gene in the Mouse Protamine Gene Cluster, Encodes a Conserved Acidic Protein That Affects Sperm Motility1PMID 18256328Read ↗

Haploinsufficiency of protamine-1 or -2 causes infertility in mice.Semantic proximity Read ↗

Viable offspring obtained from Prm1-deficient sperm in miceSemantic proximity Read ↗

Male mice heterozygous for Protamine-1 and Protamine-2 are infertile displaying sperm damage and retention of Protamine-2 precursors, transition proteins and histonesSemantic proximity Read ↗

Sperm chromatin structure and reproductive fitness are altered by substitution of a single amino acid in mouse protamine 1Semantic proximity Read ↗

Nucleoprotein Transitions During Spermiogenesis in Mice with Transition Nuclear Protein Tnp1 and Tnp2 Mutations1Semantic proximity Read ↗

Protamine sequence determines species-specific nuclear shape and histone retentionSemantic proximity Read ↗

A common protamine 1 promoter polymorphism (-190 C->A) correlates with abnormal sperm morphology and increased protamine P1/P2 ratio in infertile patients.Semantic proximity Read ↗

An SNP in protamine 1: a possible genetic cause of male infertility?Semantic proximity Read ↗

Direct visualization of pre-protamine 2 detects protamine assembly failures and predicts ICSI successSemantic proximity Read ↗

An aberrant protamine ratio is associated with decreased H4ac levels in murine and human spermSemantic proximity Read ↗

Haploinsufficiency of kelch-like protein homolog 10 causes infertility in male miceSemantic proximity Read ↗

Sleeping beauty transposon-based phenotypic analysis of mice: lack of Arpc3 results in defective trophoblast outgrowth.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.