Article
P21/ WAF1 and cyclin D1 variants and oral squamous cell carcinoma.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Mar 2008
Gomes Carolina C, Drummond Sergio N, Guimarães André L S, Andrade Carlos I, Mesquita Ricardo A, Gomez Ricardo S
Abstract excerpt
BACKGROUND: Genetic factors are known to be involved in oral squamous cell carcinoma (OSCC) development. METHOD: We evaluated a possible association between CCND1 A870G and P21/WAF1 C98A polymorphisms and OSCC, as well as the impact of the genotypes on protein immunoexpression. The study group consisted of 80 individuals with histopathological diagnosis of OSCC and the control group consisted of 80 healthy...
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