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Article

A metalloproteinase-13 polymorphism affecting its gene expression is associated with advanced stages of oral cancer.

Anticancer research - 1 Jan 2000

Vairaktaris Eleftherios, Yapijakis Christos, Nkenke Emeka, Serefoglou Zoe Charalambous, Chatzitheofylaktou Agapi, Vassiliou Stavros, Derka Spyridoula, Vylliotis Antonis, Perrea Despina, Neukam Friedrich W, Patsouris Efstratios

Abstract excerpt

BACKGROUND: Based on the known contribution of other metalloproteinases to the development of oral cancer, this study investigated the possible association of the -77A/G polymorphism in the matrix metalloproteinase-13 (MMP-13) gene with the risk of oral cancer. PATIENTS AND METHODS: The polymorphism -77A/G, which affects gene transcription, was examined in DNA samples of 161 patients with oral squamous cell...

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PMID: 18225566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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