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Article

Polymorphisms of matrix metalloproteinase-7 and -9 are associated with oral tongue squamous cell carcinoma.

Brazilian oral research - 1 Jan 2020

Nascimento George João Ferreira do, Silva Leorik Pereira da, Matos Felipe Rodrigues de, Silva Thayse Azevedo da, Medeiros Silvia Regina Batistuzzo de, Souza Lélia Batista de, Freitas Roseana de Almeida

Abstract excerpt

Matrix degradation is an important event in the progression, invasion and metastasis of malignant head and neck lesions. Imbalances, mutations and polymorphisms of MMPs and their inhibitors are observed in several cancer subtypes. The aim of this study was to evaluate the association of the MMP-7 gene promoter (181 A/G) and MMP-9 (-1562 C/T) polymorphisms in oral tongue squamous cell carcinoma (OTSCC). MMP-7...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33237244
DOI: 10.1590/1807-3107bor-2021.vol35.0019

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