Article
Association of -1171 promoter polymorphism of matrix metalloproteinase-3 with increased risk for oral cancer.
Anticancer research - 1 Jan 2000
Vairaktaris Eleftherios, Yapijakis Christos, Vasiliou Stavros, Derka Spyridoula, Nkenke Emeka, Serefoglou Zoe, Vorris Eleni, Vylliotis Antonis, Ragos Vasilios, Neukam Friedrich W, Patsouris Efstratios
Abstract excerpt
BACKGROUND: Matrix metalloproteinase-3 (MMP-3) plays a pivotal role in inflammation and thrombosis. Increased levels of MMP-3 have been correlated with progression of oncogenesis and metastasis. Inflammation-related factors have recently been found to contribute to the development of malignancies...
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