Article
[The association of MMP-13 polymorphism with susceptibility to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma].
Yi chuan = Hereditas - 1 Dec 2006
Zhang Xiao-Juan, Guo Wei, Wang Na, Zhou Rong-Miao, Dong Xiu-Juan, Li Yan
Abstract excerpt
Matrix metalloproteinase-13 (MMP-13) belongs to a family of enzymes that degrade all components of the extracellular matrix. Polymorphism in the promoter region of the MMP-13 gene may modify its transcriptional activity and protein level. This study was designed to investigate the correlation of MMP-13 A-77G single nucleotide polymorphism (SNP) with susceptibility to esophageal squamous cell carcinoma (ESCC) and...
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