Article
Association of Matrix Metalloproteinase-7 Genotypes to the Risk of Oral Cancer in Taiwan.
Anticancer research - 1 Apr 2018
Shih Liang-Chun, Li Ching-Hao, Sun Kuo-Ting, Chen Liang-Yu, Hsu Che-Lun, Hung Yi-Wen, Wu Cheng-Nan, Hsia Te-Chun, Shen Te-Chun, Chang Wen-Shin, Shih Tzu-Ching, Tsai Chia-Wen, Bau DA-Tian
Abstract excerpt
BACKGROUND/AIM: Matrix metalloproteinases (MMPs) play a critical role in inflammation and carcinogenesis, and the expression of mRNA MMP7 in oral squamous cell carcinoma tissues was higher than in the oral lichen planus or normal oral mucosa. However, the genotypic role of MMP7 has never been examined in oral cancer. Therefore, in the current study we aimed to examine the contribution of genotypic variants in the...
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