Article
Single nucleotide polymorphisms and haplotypes of MMP-14 are associated with the risk and pathological development of oral cancer.
Annals of surgical oncology - 1 Jul 2012
Weng Chia-Jui, Chen Mu-Kuan, Lin Chiao-Wen, Chung Tsung-Te, Yang Shun-Fa
Abstract excerpt
BACKGROUND: Matrix metalloproteinase (MMP)-14 is one of the pericellular collagenases to degrade extracellular matrix (ECM), which is involved to the modulation of susceptibility or clinicopathological features of a cancer. The contributions of MMP-14 on the susceptibility or clinicopathological features of certain cancers have been well documented, and the expression of MMP-14 in oral squamous cell carcinoma...
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