Article
High gene expression of matrix metalloproteinase-7 is associated with early stages of oral cancer.
Anticancer research - 1 Jan 2000
Vairaktaris Eleftherios, Serefoglou Zoe, Yapijakis Christos, Vylliotis Antonis, Nkenke Emeka, Derka Spyridoula, Vassiliou Stavros, Avgoustidis Dimitrios, Neukam Friedrich W, Patsouris Efstratios
Abstract excerpt
BACKGROUND: In the light of the recently found contribution of matrix metalloproteinases (MMPs) to oral oncogenesis, the correlation of MMP-7 with risk for oral cancer was investigated. MATERIALS AND METHODS: The MMP-7 -181A/G polymorphism in 159 German and Greek patients with oral squamous cell carcinoma and 120 healthy controls of equivalent gender and ethnicity was studied. RESULTS: The detected carrier...
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