Article
Polymorphisms of the IL12B and IL23R genes are associated with psoriasis.
The Journal of investigative dermatology - 1 Jul 2008
Nair Rajan P, Ruether Andreas, Stuart Philip E, Jenisch Stefan, Tejasvi Trilokraj, Hiremagalore Ravi, Schreiber Stefan, Kabelitz Dieter, Lim Henry W, Voorhees John J, Christophers Enno, Elder James T, Weichenthal Michael
Abstract excerpt
Psoriasis is a common inflammatory and hyperproliferative skin disease with a multifactorial genetic basis. A recent study reported that psoriasis was associated with the IL12B haplotype rs3212227 (3'-untranslated region)-rs6887695 (60 kb, 5') and the IL23R haplotype rs7530511 (L310P)-rs11209026...
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