Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation at IL12B, IL23R and IL23A is associated with psoriasis severity, psoriatic arthritis and type 2 diabetes mellitus.

Journal of dermatological science - 1 Sept 2014

Eirís Noemí, González-Lara Leire, Santos-Juanes Jorge, Queiro Rubén, Coto Eliecer, Coto-Segura Pablo

Abstract excerpt

BACKGROUND: Common DNA variants in IL12B, IL23R and IL23A have been associated with an increased susceptibility to psoriasis (Ps) and psoriatic arthritis (PsA). Metabolic comorbidities and cardiovascular risk factors have also been associated to both Ps and PsA. OBJECTIVE: To analyze the effect of single nucleotide polymorphisms (SNPs) previously linked to Ps (IL12B rs6887695 and rs3212227, IL23R rs2201841 and...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Psoriatic
Share to Comorbidity
Share to Diabetes Mellitus, Type 2
Share to Interleukin-12 Subunit p40
Share to Introns
Share to Psoriasis
Share to Receptors, Interleukin
Share to Spain

Source

Identifiers

PMID: 24957500
DOI: 10.1016/j.jdermsci.2014.05.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation at IL12B, IL23R and IL23A is associated with psoriasis severity, psoriatic arthritis and type 2 diabetes mellitus.PMID 24957500Read ↗

Polymorphisms of the IL12B and IL23R genes are associated with psoriasis.Semantic proximity Read ↗

Investigation of association of the IL12B and IL23R genes with psoriatic arthritis.Semantic proximity Read ↗

Association study in Romanians confirms IL23A gene haplotype block rs2066808/rs11171806 as conferring risk to psoriatic arthritis.Semantic proximity Read ↗

Association of IL23R polymorphisms with psoriasis and psoriatic arthritis: a meta-analysis.Semantic proximity Read ↗

IL-23 serum levels and IL23R polymorphisms in psoriasis: a meta-analysis of susceptibility and severity.Semantic proximity Read ↗

Resequencing of the IL12B gene in psoriasis patients with the rs6887695/rs3212227 risk genotypes.Semantic proximity Read ↗

A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes.Semantic proximity Read ↗

IL12B, IL23A, IL23R and HLA-C*06 genetic variants in psoriasis susceptibility and response to treatment.Semantic proximity Read ↗

Polymorphisms in the IL-12β and IL-23R Genes Are Associated with Psoriasis of Early Onset in a UK CohortSemantic proximity Read ↗

Associations between interleukin-23R and interleukin-12B polymorphisms and psoriasis susceptibility: a meta-analysis.Semantic proximity Read ↗

TNFAIP3 and IL12B gene polymorphisms associated with psoriasis vulgaris in an Egyptian cohort.Semantic proximity Read ↗

Psoriasis is associated with pleiotropic susceptibility loci identified in type II diabetes and Crohn disease: Table 1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.