Article
Replication of association between interleukin-23 receptor (IL-23R) and its ligand (IL-12B) polymorphisms and psoriasis in the Chinese Han population.
Human immunology - 1 Dec 2010
Wu Yumei, Lu Zhiyong, Chen Yingwei, Xue Feng, Chen Xiaoyin, Zheng Jie
Abstract excerpt
Psoriasis is an inflammatory skin disease with a multifactorial genetic basis. A recent genome-wide association study identified several psoriasis-predisposing loci, including IL-12B, which encodes the common p40 subunit of interleukin (IL)-12 and IL-23 and the IL-23 receptor gene (IL-23R). To in...
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