Article
Investigation of association of the IL12B and IL23R genes with psoriatic arthritis.
Arthritis and rheumatism - 1 Dec 2008
Filer Charlotte, Ho Pauline, Smith Rhodri L, Griffiths Christopher, Young Helen S, Worthington Jane, Bruce Ian N, Barton Anne
Abstract excerpt
OBJECTIVE: Recent reports have confirmed association of single-nucleotide polymorphisms (SNPs) mapping to the interleukin-23 receptor (IL-23R) and IL-12beta genes with psoriasis susceptibility. The aim of this study was to determine whether these variants are also associated with susceptibility to psoriatic arthritis (PsA). METHODS: Two IL23R SNPs (rs7530511 and rs11209026) and 2 IL12B SNPs (rs3212227 and...
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