Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL-23 serum levels and IL23R polymorphisms in psoriasis: a meta-analysis of susceptibility and severity.

BMC immunology - 18 Feb 2026

Ahmadipanah Saboor, Shariat Rad Parand, Montaseri Maryam, Nemati Houshang, Sadeghi Masoud, Ramezani Mazaher

Abstract excerpt

BACKGROUND: Psoriasis is an immune-mediated inflammatory disease with a strong genetic basis. The Interleukin-23 (IL-23)/Th17 axis is central to its pathogenesis. While IL-23 is established, studies on systemic serum levels and IL23R gene polymorphisms yielded varied results. Our study clarified these associations through a systematic review and meta-analysis. METHODS: A systematic search was performed to find...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-23

Share to Odds Ratio

Share to Polymorphism, Single Nucleotide

Share to Psoriasis

Share to Receptors, Interleukin

Share to Severity of Illness Index

Source

Open in PubMed Open full text

Identifiers

PMID: 41709148
DOI: 10.1186/s12865-026-00814-y
PMCID: PMC13019827

Genes

IL23R

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL-23 serum levels and IL23R polymorphisms in psoriasis: a meta-analysis of susceptibility and severity.PMID 41709148Read ↗

Evaluation of interleukin-23 receptor (IL-23R) gene polymorphisms and serum IL-23 levels in patients with psoriasisSemantic proximity Read ↗

Associations between interleukin-23R and interleukin-12B polymorphisms and psoriasis susceptibility: a meta-analysis.Semantic proximity Read ↗

Association of IL23R polymorphisms with psoriasis and psoriatic arthritis: a meta-analysis.Semantic proximity Read ↗

IL12B, IL23A, IL23R and HLA-C*06 genetic variants in psoriasis susceptibility and response to treatment.Semantic proximity Read ↗

Role of IL-23 in the pathogenesis of psoriasis: a novel potential therapeutic target?Semantic proximity Read ↗

Investigation of association of the IL-12B and IL-23R genetic variations with psoriatic risk in a South Indian Tamil cohort.Semantic proximity Read ↗

Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.Semantic proximity Read ↗

Polymorphisms in the IL-12β and IL-23R Genes Are Associated with Psoriasis of Early Onset in a UK CohortSemantic proximity Read ↗

Polymorphisms of the IL12B and IL23R genes are associated with psoriasis.Semantic proximity Read ↗

Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.Semantic proximity Read ↗

The IL-17/IL-23 Axis and Its Genetic Contribution to Psoriatic Arthritis.Semantic proximity Read ↗

A Pharmacogenetic Study of Psoriasis Risk Variants in a Greek Population and Prediction of Responses to Anti-TNF-α and Anti-IL-12/23 Agents.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.