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Article

Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.

Human genetics - 1 Sept 2007

Capon Francesca, Di Meglio Paola, Szaub Joanna, Prescott Natalie J, Dunster Christina, Baumber Laura, Timms Kirsten, Gutin Alexander, Abkevic Victor, Burden A David, Lanchbury Jerry, Barker Jonathan N, Trembath Richard C, Nestle Frank O

Abstract excerpt

Psoriasis is an inflammatory skin disorder that is inherited as a multifactorial trait. Genetic analyses have repeatedly identified a primary disease susceptibility locus lying within the major histocompatibility complex (MHC), on chromosome 6p21. A small number of non-MHC susceptibility loci have also been identified. These regions tend to overlap with susceptibility intervals for Crohn's disease and atopic...

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PMID: 17587057
DOI: 10.1007/s00439-007-0397-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.PMID 17587057Read ↗

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