Article
TNFAIP3 and IL12B gene polymorphisms associated with psoriasis vulgaris in an Egyptian cohort.
Journal of the European Academy of Dermatology and Venereology : JEADV - 1 Jul 2015
Haase O, Mosaad H, Eldarouti M A, Elramly A Z, Samir N, Abdelhady M M, Samir M, El-Gharib I, Salah S, El-Shennawy F A, Mosaad Y, Elwan N, Salem H, Abdelgaber S, Recke A, Möller S, Zillikens D, Ibrahim S
Abstract excerpt
BACKGROUND: Psoriasis vulgaris is a common chronic inflammatory skin disease. Development of early onset psoriasis is, to some extent, genetically determined and a strong association with the major histocompatibility complex HLA-Cw6 has been demonstrated. The use of genome-wide association studies has highlighted novel genes associated with the development of psoriasis as IL12B, IL23R, TNFAIP3 and IL13 for...
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