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Article

Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population.

Pharmacogenetics and genomics - 1 Jan 2008

Zhang Laxi, Ding Hu, Yan Jiangtao, Hui Rutai, Wang Wei, Kissling Grace E, Zeldin Darryl C, Wang Dao Wen

Abstract excerpt

OBJECTIVE: Epoxyeicosatrienoic acids have been recognized for their protective effects on the cardiovascular system. This study investigated whether two common polymorphisms in genes believed to be influential in regulating circulating levels of epoxyeicosatrienoic acids, namely cytochrome P450 2J2 (CYP2J2) G-50T and soluble epoxide hydrolase (EPHX2) G860A, were associated with ischemic stroke risk in a Chinese...

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Source

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Identifiers

PMID: 18216721
DOI: 10.1097/FPC.0b013e3282f313e8
PMCID: PMC2367218

Genes

EPHX2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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