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Article

CYP2C8 rs17110453 and EPHX2 rs751141 two-locus interaction increases susceptibility to ischemic stroke.

Gene - 1 Jul 2015

Yi Xingyang, Zhang Biao, Wang Chun, Liao Duanxiu, Lin Jing, Chi Lifen

Abstract excerpt

AIMS: Ischemic stroke (IS) is a multifactorial disease caused by a combination of environmental risk factors and genetic susceptibilities. However, few studies have assessed the effects of gene-gene interactions among cytochrome P450 (CYP) pathway genes on the risk of stroke. The present study investigated the association of seven variants of six CYP pathway genes with IS in a Chinese population. MAIN METHODS: A...

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Identifiers

PMID: 25839935
DOI: 10.1016/j.gene.2015.03.068

Genes

EPHX2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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