Article
Association between polymorphisms of CYP2J2 and EPHX2 genes and risk of coronary artery disease.
Pharmacogenetics and genomics - 1 Aug 2011
Xu Yujun, Ding Hu, Peng Jia, Cui Guanglin, Liu Lei, Cianflone Katherine, Wang Dao Wen
Abstract excerpt
OBJECTIVE: Common polymorphisms within cytochrome P450 2J2 (CYP2J2) and epoxide hydrolase 2 (EPHX2), which are involved in the generation or hydrolysis of epoxyeicosatrienoic acids, may determine susceptibility to the development of cardiovascular disease. To derive a more precise estimation of their relationship, we undertook a case-control study as well as a meta-analysis to assess possible associations of...
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