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Article

Genotype dependence of peptide-based immunoassays for the detection of HCV core antibodies.

Journal of medical virology - 1 Mar 2008

Muerhoff A Scott, Gutierrez Robin, Kyrk Charles, Leary Thomas, Schlauder George, Dawson George, Desai Suresh M

Abstract excerpt

Detection of hepatitis C virus (HCV) antibodies is partially influenced by the genotype of the infecting isolate. Immunoassays using genotype-1a-derived recombinants or peptides results in diminished reactivity among individuals infected with heterologous genotypes. We examined the magnitude of this effect on detection of core antibodies by using genotype-1a-derived core peptide immunoassays to test 254 HCV...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18205228
DOI: 10.1002/jmv.21082

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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